Paul C.H. Li
B.Sc., Chemistry and Physics, University of Hong Kong
M.Sc., Ph.D., Analytical Chemistry, University of Toronto
Professor
Simon Fraser University
For what Dr. Li has read and written about books, click here.
Single-cell assay, nanomaterial-based nucleic acid assays, chemical analysis of natural product compounds, artificial intelligence.
​
We are interested in carrying out various chemical and biochemical analysis which are enhanced by the use of modern bioanalytical techniques, microfluidic nanotechnology and artificial intelligence.
​
In particular, we are interested in:​
-
Single-cell based assays in microfluidic lab-on-a-chip: calcium mobilization in yeast cells, cardiac myocytes and glioma cells; multidrug resistance (MDR) reversal in cancer cells (leukemia, prostate, ovarian, lung, breast, glioma, MDCK)
-
Nucleic acid tests for biological samples (e.g. plant fungal DNA, salmon DNA samples, human KRAS oncogene, EGFR gene, ginseng DNA, and viral RNA)
-
Nanobiooarray chips for analysis of biological samples (e.g. for influenza antibody, cytokine/interleukin samples)
-
Microchip synthesis of radiotracers (C-11 methionine, C-11 ralcopride, F18 compounds) for positron emission tomography (PET) imaging applications
-
Advanced nanomaterials for chemical testing (Inverse opal film, photonic crystals, structural color, chemical sensors)
-
Characterization of cannabinoids (THC, CBD) and terpenes in Cannabis samples (HP-LC, GC-MS, genotyping, intracellular calcium)
-
Use of machine learning methods (e.g. PCA, R) to enhance bioanalytical chemical assays.