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Research

Li group research 2024.jpg

A: Bioanalytical chemistry and artificial intelligence

1.    Principal component analysis (PCA) of chemical data using R.

2.    Docking study of protein receptors and small molecules using Autodock.  

A: Nanomaterial-based chemical sensing
1. Chemical sensing of gas-oil mixture
2. Detection of ethanol

Nano Research, 2015, 8, 3922-3933

Anal, Biochem, 2014, 448, 58-64.

C: Analysis of single biological cells (cancer cells, heart muscle cells, blood cells) on a microfluidic chip.

1.    Analysis of bioactive compounds derived from natural sources, e.g. licorice, and blueberry, on single cancer cells.

2.    Inhibition effect on the multi-drug resistance performed on AML patient samples.

3.    Isolation and measurement of prostate cancer cells among blood cells.  

Biomicrofluidics 9, 064014 (2015), 1-18.

Anal. Chem., 2016, 88 (11), pp 5680-5688

D:Chemical separations of natural products

1. HPLC separations of blueberry compounds

2. LCMS analysis of ginseng compounds

ISRN Anal. Chem. 2014, 486842, 1-8.

Anal. Methods, 2012, 4, 864-868.

B: NanoBioArray Chips for DNA-based diagnosis

1. Detection of Greenhouse Fungal Pathogenic DNA

2. Gold nanoparticles-assisted single-base pair discrimination achieved at room temperature, featured in Science Daily.

3. KRAS genotyping based on DNA hybridization

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